Gadolinium/terbium hybrid macromolecular complexes for bimodal imaging of atherothrombosis

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Gadolinium/terbium hybrid macromolecular complexes for bimodal imaging of atherothrombosis.

We developed a fluorescence imaging microscope system intended for the localization within artery slices of a gadolinium-based macromolecular biospecific magnetic resonance (MR) contrast agent used for the visualization of atherothrombosis. As the contrast agent is not initially fluorescent, we substitute some gadolinium ions for terbium ions to make them fluorescent while preserving their chem...

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ژورنال

عنوان ژورنال: Journal of Biomedical Optics

سال: 2017

ISSN: 1083-3668

DOI: 10.1117/1.jbo.22.7.076004